There were Chelsea players involved in World Cup qualifiers while another in an Olympic play-off.
Willian and Oscar failed to win their crucial match and are now struggling with going through the Final Stage. Brazil are now 6th in the table and the top four teams automatically progress to the finals, with the fifth-placed side entering a play-off.
Brazil scored two goals in the last 11 minutes to earn a point away from home against Paraguay in World Cup qualifying; Willian played the full game even scoring the first goal, while Oscar remained on the bench.
Juan Cuadrado, on loan at Juventus, played with Colombia in the impressive 3-1 win over Ecuador.
Michael Hector, who is on loan at Reading, played the full game for Jamaica as they were beaten 3-0 by Costa Rica.
Matt Miazga started for the US Under23 but was sent off when, as the last man, he was adjudged to have denied Colombia a goalscoring opportunity.